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- SPC Emulator GBA
- SPD Loader Wii
- SQLDisplay
- SQRXZ 2 PSP
- SQRXZ 3 PSP
- SQRXZ 4 PSP
- SRAM
- SRLoader
- SRSG PSP
- SRS Screen Repair Set PSP
- SRS Vita
- SS6PlayerForGBA
- SSBUStageInjector Switch
- SSBU Amiibo Editor Switch
- SSEQ Player i
- STARDUST for PSP
- STEINSGATE 0 RenPSP Port
- STEPPER 3DS
- STEPPER GBA
- STO
- STUNNER GB
- ST Sound Advance GBA
- STuning PSP
- SUPER Goomba GBA
- SUPER IMPOSTOR BROS GB
- SV Capture PSP
- SV Image Injector Switch
- SWITCHBOOT UF2 and FUSEE UF2 for Switch
- SXOS Hidden Emunand Backup Tool Switch
- SXOS ROMMENU Switch
- SXPD Switch
- SX Google Drive Token Generator Switch
- SX OS - Cheat Assistant Switch
- SX OS Switch
- SYASokoban Wii
- SYNC SIMPLE PSVita
- SYS-CW Switch
- SYS-HTTP Switch
- S World GB
- Sa0tour0 Vita
- SaGa 2 - Hihou Densetsu - Goddess of Destiny Save Editor
- SaGa 2 - Legend of the Relics - Goddess of Destiny
- SaGa 3 - Rulers of Time and Space - Shadow or Light
- SaGa Scarlet Grace - Ambitions Undub Switch
- Sabacc Basics PSP
- Sabacc Portable PSP
- Sabinov GB
- Sadmenu Wii
- SafeA9LHInstaller 3DS
- SafeB9SInstaller 3DS
- SafeCTRTransfer 3DS
- SafeSysUpdater 3DS
- Saga Scarlet Grace English Vita
- Saikoro Psycho - Seventh Heaven Switch - English Translation
- Sailor Moon - La Luna Splende
- Sailor Moon R Plus PSP
- Saint Seiya - The Phoenix Returns GB
- Saints Row - Undercover PSP
- Sakura Succubus 2 Vita
- Sakura Succubus 3 Vita
- Sakura Succubus 4 Vita
- Sakura Succubus Vita
- Sakurasou no Pet na Kanojo PSP - English Translation
- SaltFW 3DS
- Salt And Sanctuary Mod Vita
- SaltyNX-Tool Switch
- SaltyNX Switch
- SaltySD 3DS
- SamCoupeX Xbox
- Sam Fusee Launcher Internal Switch
- Sam Mallard - The Case of the Missing Swan GB
- Sam and Max The Hangman Game
- SameGame Wii
- Same Game GBA
- Same Or Not GB
- Samurai Kirby
- Samus Returns - Amiibo Unlocker 3DS
- Sand GB
- Sand Game Demo
- Sand Traps Wii
- Sandbox Engine DS-DSi
- Sandbox Engine DSi-Hybrid
- Sandbox PSP
- Sandscape
- SangoKuro 3DS
- SanicBall Vita
- Sanic Ganerashons DS
- Santa's Bad Luck
- Santa's Challenge
- Santa's Factory
- Santa's Flight
- Santa Claus journey GB
- Santa Escapes The Labyrinth Of Presents GBA
- Santa Rush
- Santa Saves Xmas GBA
- Santa vs Martians
- Santas Chimney Challenge GBA
- Santas Robot Helper
- Santas Sweatshop GBA
- Saphir GBA
- Sar Wii
- Sass step-girl GB
- SatFinder Portable PSP
- Satella Zone 3DS
- Sator/Arepo/Tenet DS
- Satsuma Yoyo GBA
- Saturn-FPKG PS4
- Saturn2NSP Switch
- Saulfabreg AIO Wii VC iNJECT Tools Pack
- Sauver Papa Nöel
- SavReceiver
- SavSend
- Save3DS
- SaveDataMgr PSP
- SaveFileConverter Wii
- SaveGame Manager GX Wii
- SaveHacker PSP
- SaveMii InjectMod Wii U
- SaveMii Wii U
- SaveMii Wii U - WUT Port
- SaveTheCastle PSP
- Save Cloud Vita
- Save Data Copy Tool 3DS
- Save Data Manager and Editor 3DS
- Save Scummer PSP
- Save The Bees Vita
- Save The Castle Wii
- Save The Guy From The Burning Building
- Save The Puppies GB
- Save The Scene PS4
- Save The Scene Vita
- Save Util GBA
- Save the Sun PSP
- SavedataPlus Vita
- Savegame Deemer PSP
- Savegame Extractor Wii
- Savegame Installer Wii
- Savegame Manager Wii
- Savepi GB
- Savezelda Wii
- Saviine Wii U
- Saving Ichigo: Brawler PSP
- Saving Santa
- Savsender
- SavvyManager 3DS
- Sawyers Stories - Time For The Chickens to go to Sleep GBA
- Sawyers Stories - Time For The Chickens to go to Sleep Wii
- Sawyers Stories - Time for The Chickens to go to Sleep 3DS
- ScanLine PSP
- Scanboy GBA
- Scanline Offset Shader 3DS
- Scape Wii
- Scarlett Witch GB
- SceDs3Ext Vita
- SceKernelModuleDumper Vita
- SceShaccCgExt Vita
- SceShutterSoundPlayDisable Vita
- Schism Tracker Wii
- School English PSP
- Schusstest
- Sci-Fi Yoyo PSP
- Scogger
- Scogger PSP
- Scogger Wii
- Scoglionario
- Scorched PSP
- Scrabble Assistant DS
- Scrabble Dictionary
- Scrabble Dictionary GBA
- Scrabble Helper PSP
- Scramble GB
- Scramble Save Editor Switch
- Scrambl’d GB
- Scratch 'n' Match
- Screen-NX Switch
- ScreenInfo 3DS
- ScreenTester-NX Switch
- Screen Defender PSP
- Screen Repair Set PSP
- Screenie Vita
- Screenshot-merge 3DS
- Screenshot Enabler Vita
- Screenshot Wii U
- Screenshotbmp PSP
- Scribble Jump DS
- Scrilla Forilla GBA
- Scrolls Of Fire GBA
- Scrtool 3DS
- Scrum GBA
- Scrup 3DS
- Scrybble GBA
- Sculptor Vita
- ScummVM 3DS
- ScummVM Builder Vita
- ScummVM DS
- ScummVM Switch
- ScummVM Vita
- ScummVM Wii
- ScummVM Xbox
- Scummvm Bubble Booter Vita
- Scummvm Wii
- Sd Explorer Wii
- Sdl-Hello Switch
- Sdl2 Vita
- SdmcNX Switch
- SeSnake GBA
- SeaWolf
- Sealed Bite Switch
- Seaquest DS
- Search Eye DS
- Searching For My Identity GB
- Season Stacker GBA
- Season of Henkaku Vita
- SecondDisplay PSP
- Secret Collect
- Secret Hordes
- Secret Maryo Chronicles X Xbox
- SecureText PSP
- Seek And Recharge
- Sega PD Games GBA
- Seghers Wii.git
- Sego/Sarko
- Seismometer PSP
- SendElf Wii
- Senet Wii
- Senjou no Valkyria 3 - Extra Edition Translation PSP
- Seno DS
- Senran Kagura Peach Ball 60 FPS Mod Switch
- SensitiveDS
- SensitivePSP
- SensitiveX Xbox
- SensorMii Wii
- Sensormii Wii
- Septerra Core Legacy of the Creator Vita
- Sepulka PSP
- SeqMp3Player Vita
- Serious Engine Switch
- Serp GBA
- Serpedelic GB
- Serpent Apocalypse GB
- SerpientePX PSP
- Serve N Go PSP
- SetDS
- SetRegion-GUI Vita
- Setgool PSP
- Setris
- Setsuzoku no Puzzle
- Settings Editor GUI Wii
- Settings Editor Gui Wii
- Severen GB
- Sexy Blackjack Trainer
- Sexy Blackjack Trainer II
- SfxMixerTT-PSP
- Sg bump GBA
- Sgt. Helmet Zero DS
- ShaRKBR33D Vita
- Sha Shlik GBA
- Shaded Bar Demo GB
- Shades On
- ShadowNAND 3DS
- ShadowPong PSP
- ShadowX Xbox
- Shadow Dragon - Always Recruit Norne
- Shadow Dragon - Full Content Patch
- Shadow Dragon - Online Shop Exclusive Items Integrated into Normal Gameplay
- Shadow Dragon - Prologue in Hard Modes
- Shadow Dragon - Updated Gaiden Requirements Removal Patch
- Shadow Gulch GBA
- Shadow Nights GB
- Shadow Warrior PSP
- Shadow of the Wurst GBA
- ShallowSea-Toolbox Switch
- ShallowSea Switch
- Shameless 3DS
- Shaolin's Road GB
- ShareNX-Overlay Switch
- SharedFb-PSV Vita
- SharedFontTool 3DS
- Shared Font Dumper Switch
- Shark! Shark! 3DS
- Shark! Shark! Switch
- Shark! Shark! Vita
- Sharkf00d Vita
- Sharkive 3DS
- Sharkive Switch
- Sharpii-NetCore Wii
- Sharpii Netcore Wii
- Sharpii Wii
- Sharpscale Vita
- Shasciw Switch
- Shattered Pixel Dungeon Switch
- SheepSOS
- Sheep Goes Left DS
- Sheep Kaboom GB
- Sheep Leap GB
- Sheep Machine PSP
- Sheep it up GB
- Sheeparoids GBA
- Sheikah All-In-One CFW Switch
- ShellSecBat Mod Vita
- ShellSecBat Vita
- Shell Plugin Package PSP
- Shell SYSTEM PSP
- Shellbat Codiak Mod Vita
- Shellbat Mod Vita
- Shellbat Vita
- Shelling PSP
- ShepHard Vita
- Sherlock - A Study in Scarlet GB
- Shield Bouncer GB
- Shield Warrior VII GB
- Shin-chan Adventures in Cinemaland GBA
- Shin Bokura no Taiyou - Gyakushuu no Sabata GBA
- Shin Megami Tensei - Strange Journey Redux Restoration Mod 3DS
- Shin Megami Tensei III - Nocturne HD Remaster Save Editor Switch
- Shin Megami Tensei V 60 FPS Graphics Mods Switch
- Shin Megami Tensei V Save Editor Switch
- Shine's Snake PSP
- Shining Blade PSP - English Translation
- Shining Fantasy Preview PSP
- Shining Resonance Refrain Save Editor Switch
- Shinseiki Evangelion: Girlfriend of Steel Portable PSP - English Translation
- Shinseiki Evangelion: Koutetsu no Girlfriend 2nd Portable PSP - English Translation
- Shiny Red Tank Wii
- Ship Of Harkinian - Ocarina Of Time For Switch
- Ship of Harkinian Wii U
- Shippy1984X Xbox
- Shiromino Switch
- Shiromino Vita
- Shisen-Sho PSP
- Shmup 3D
- Shmup NDS
- Shock Lobster GB
- Shocker PSP
- Shockolate - System Shock Switch
- Shockolate Vita
- Shogi Advanced GBA
- ShogunTool Switch
- Shoop da whoop VS. Stick-man
- Shoot2d
- Shoot4Fun PSP
- ShootMii Wii
- Shoot Watch Hudson PSP
- Shoot the Warriors PSP
- Shoot the X GB